Effect of premature termination of translation on mRNA stability depends on the site of ribosome release.
نویسندگان
چکیده
منابع مشابه
Effect of premature termination of translation on mRNA stability depends on the site of ribosome release.
Translational stop codons were introduced at various locations in the protein-coding regions of the monocistronic bla and ompA gene transcripts of Escherichia coli, and the decay characteristics of the upstream and downstream mRNA segments were analyzed. Premature termination of translation at codon position 26 reduced the stability of both the translated and ribosome-free segments of bla mRNA,...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1987
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.84.14.4890